LuckCong's Health Blog

At present, the treatment of chronic hepatitis B is a worldwide problem. Many patients with chronic hepatitis B, the use of multi-drug treatment, but the effect is not clear that the overall incidence of the disease recurring. Have become chronic hepatitis B, and the structure of the hepatitis B virus infection means immune characteristics and other factors are closely related. First of all, people infected with hepatitis B virus, hepatitis B virus in the blood have a hard protein shell. As a result, the treatment of hepatitis B drug is difficult to have a direct effect on the virus and must rely on the body's immune function. Second, the hepatitis B virus replication in liver cells for the treatment of small molecule drugs to be material to enter the liver cells play an antiviral effect. Hepatitis B virus in human liver tissues other than the average incubation period of 90-120 days, the anti-viral drugs to be useful, must be given the necessary treatment, the treatment system. Third, the hepatitis B virus in some drugs, the virus gene mutation occurs, the resistance or immune evasion. Thus in the choice of drugs should be careful. Fourth, the hepatitis B virus infection after liver cells, with the extension of the course, the virus may be related to liver cells have a gene integration. In the event of such a phenomenon, the treatment will significantly increase the degree of difficulty. As a result, the treatment of hepatitis B must be timely. In addition, the vertical transmission of hepatitis B vulnerable to the formation of immune tolerance. Infected with hepatitis B virus infection in the mother of the fetus through the placenta, the birth of a child, because of inadequate development of the immune system, immune function is not complete, can not identify the hepatitis B virus, resulting in hepatitis B virus infection. Moreover, the hepatitis B virus replication of the model is different from the virus, the virus will replicate the original template, such as the formation and stability of the liver and stored in the cell nucleus, the general anti-viral drugs on the template invalid, after the drug in patients with hepatitis B The disease often occur repeatedly.