LuckCong's Health Blog

Hepatitis is a serious harm to the broad masses of the people of a common disease. Among them, as viral hepatitis A, according to the Ministry of Health survey, from 1992 to 1995, China's population for hepatitis A infection rate 80.9%; hepatitis B infection rate was 57.6 percent; accordingly projections about our 970,000,000 People have been infected with hepatitis A virus; 690,000,000 people have been infected or are infected with hepatitis B virus, 1.2 million people carry hepatitis B virus, the virus inflammation has become a very serious public health problem should be of great importance to the community, to strengthen prevention To reduce the incidence and prevalence of control. We are here to tell us about the hepatitis B virus and hepatitis B-related knowledge: Hepatitis B Virus DNA belonging to the virus, with a diameter of 42nm complete virus particle, also known as Dane particles, at shells and the core of two parts, including Shell and the former surface antigen S gene product, was shell diameter of 22nm and possession of ball Central, the excess protein is a Virus. No infectious case itself. Core ring with the double-stranded DNA, the entire core of the core antigen (HBsAg), e antigen is the core fragment (HBeAg). Hepatitis B virus does not directly damage liver cells, liver injury is caused by the body's immune response. Hepatitis B virus infection in the liver cells, liver cells can change the surface of the antigen and to stimulate T cells become sensitized lymphocytes, the body also had a corresponding anti-liver cell membrane antigen antibody, they attack with the virus Liver cells, to clear the virus at the same time, leading to the breakdown of liver cells, degeneration and necrosis, the normal immune response are generally expressed in acute icterohepatitis in the recovery of immune function enough to clear the virus and the body was recovered. Immune function over The strong can be a severe hepatitis, because a large number of viruses have been eliminated at the same time, a wide range of liver cells have been destroyed. If the body-specific cell-mediated immunity and humoral immune deficiencies are, to reduce the cycle of T cells, the lack of anti-HBs, and therefore can not Clear the virus, inhibiting their reproduction, and some liver cells in the sensitized cells under constant is damaged, Buyu make lasting changes, the formation of chronic active hepatitis. Minor damage to persons with chronic persistent hepatitis; if the patient's T cells Very poor function, the virus can be free to enter and leave the cell, continued proliferation of reproduction, a large amount of HBsAg, but the liver cell degeneration and necrosis very minor, to become carriers of HBsAg. Pathogenesis of hepatitis B and immune response are intertwined and complicated, and the prevention of hepatitis B the most effective way is to understand the source of infection and transmission. The source of infection of hepatitis B: acute hepatitis, chronic hepatitis patients and virus carriers. The route of transmission of hepatitis B: 1. Spread of blood and blood products (transfusion and injection); 2. Iatrogenic spread (syringes, needles, blood collection devices, acupuncture needles, surgical blades, Oral equipment, endoscopy, etc.); 3. Close contact (hepatitis B patient's blood, saliva, tissue fluid, semen, urine can be detected HBV, therefore, will be available through sexual intercourse, such as hepatitis B virus to each other); 4. Mother to child transmission (most of them in the Birth, with hepatitis B virus from the mother's vaginal secretions, amniotic fluid, the blood of newborns into the mouth and nose, stomach infection caused by the other part of the breast-feeding for infants and lead to kiss). Prevention of Hepatitis B: 1. Hepatitis B patients and virus carriers should pay attention to the isolation (with separate sanitary), the room can be equipped with a little potassium permanganate, formaldehyde, about 70ml, can produce a sharp smoke, to close Indoor smoke doors and windows goods; 2. Relating to the management sector (government departments to deal with sanitation and food hygiene to a unified monitoring and management); 3. The management of blood donors; 4. To strengthen the management of iatrogenic transmission; 5. Hepatitis B vaccine Immunization, safe and effective vaccine made to protect the rate of 90%.