LuckCong's Health Blog

58th Session of the United States for the study of liver disease reported that the annual meeting (Nov. 2-6) Your Liver, Your life care of the liver, the value of life Participate in the study of liver disease in the United States will be felt Zhu Yun dove our reporter Liver, carrying the weight of life. It per minute in silence to the completion of more than 5000 kinds of important functions, in order to maintain the normal operation of the body. However, the vital organs, is often overlooked. Perhaps it is because of the damage, often unknowingly taken place, it is perhaps the course, is often a long and gradual ... .... "Your Liver, Your life", this is my liver disease in the United States this year will see the field, the deepest feelings of a slogan. In the current President of the General Assembly and Gregory J. Gores, a professor of communication, I am even more deeply into the study of liver disease in the United States is committed to raising public awareness of liver disease in its efforts. By the same token, I also shared with him this shows the annual meeting of the diagnosis and treatment of liver disease research and achievements in the field. Liver disease at this annual meeting, regardless of non-alcoholic fatty liver disease (NAFLD), viral hepatitis, liver fibrosis / sclerosis, or liver cancer targeted therapy, the treatment after liver transplantation and other fields, there are new The results of the research and development of new drugs and the report, which reflects the latest developments in the field of liver disease. As the Gores, a professor talking about some of the findings of the disease so that people understand the concept has changed, and some of the results of our new means of treatment, or bring new hope. Gores, a professor talking about, NAFLD has become a chronic liver disease and liver enzyme abnormalities of the main causes of the continuing, but the impact on the survival rate of patients with NAFLD and quality of life of the main factors is not their own liver disease (cirrhosis), but the metabolic syndrome and its Related complications. More and more studies confirm that, NAFLD is usually combined with the existence of glucose and lipid metabolism disorder, and even some academics have suggested, NAFLD can be used as metabolic syndrome and type 2 diabetes in the early predictor. As a result, monitoring of serum liver enzymes (ALT, AST, GGT) is not only the traditional sense of liver function monitoring, the significance and importance, like on blood lipid and blood pressure monitoring, and other health indicators. "Know Your ALT" is a 2006 U.S. study of liver disease will be launched a campaign aimed at arousing the Government, the medical profession and public health importance of the liver. Gores also introduced to the professor, viral hepatitis has been the world's countries, particularly in Asia, the heavy burden of disease, but in recent years as anti-HBV and anti-HCV drug research as well as anti-HBV vaccine widely used, the incidence of liver cancer has Lower. According to the Organ Transplant Center to register the data statistics, in recent years as a result of HBV infection need for liver transplantation has been to reduce the number of people, which reflects one aspect of an effective anti-HBV treatment in recent years with results. In the report on the annual meeting of entecavir for 4-year resistance, anti-interferon in the treatment of HBV and HCV in the area continued to deepen, as well as studies SHARP Sorafenib in the treatment of advanced liver cancer achieved a breakthrough effect Have enabled us to be more confident in the future of the treatment. Have a healthy liver, healthy body is an important foundation. Your Liver, Your life. Care of the liver, liver to maintain health, stay away from those affected liver health habits and behavior of the bad habits that promote a healthy lifestyle may reduce liver disease and enhance human health in a short-cut.

Following the 2006 Andy Lau as the Chinese Foundation for Hepatitis B prevention and control publicity ambassador, Andy Lau also recently shot public service announcements, write "Baby darling," the promotion of performing arts at the same time focus on the promotion of social care and hepatitis B patients. With the heat away gradually, is about to usher in another high school and employment. Some of us, or our children, friends, but also because of illness and confusion. We believe that understanding can only understand in order to allow the community more harmonious big family happy. Here, we are invited to the Shanghai Ruijin Hospital Director Professor Xie Qing Chuan Ranke and the community together to talk science. According to statistics, China's hepatitis B virus, about 120,000,000 people living with chronic hepatitis B patients about 30,000,000 cases each year, about 350,000 patients die of HBV-related chronic diseases, how to effectively reduce the infection rate of hepatitis B virus, at the same time Further improve the treatment of patients with hepatitis B is a topic of great concern, and the scientific understanding of the hepatitis B virus-related knowledge to solve this problem is a prerequisite. Immune a seesaw battle between the virus and When the hepatitis B virus into the human body, the hepatitis B virus, only to the liver, "Qingyouduzhong" medically known as the tropic of the liver virus, the virus through our circulatory system to quickly gather the liver, liver cells into the substantial copying. Typically, the foreign substances such as viruses and bacteria invasion, the body's immune system will immediately begin just outside of biological warfare, hoping to completely remove the invaders. In the adult period, this mechanism is very sound, even if infected with the hepatitis B virus, most people can rely on the immune system and clear the virus, which was recovered. However, in infants and young children during the course of this encounter will be a big problem. As the host immune newborn is not fully developed, easily mistaken for the hepatitis B virus itself, and thus the immune system can not identify and clear the hepatitis B virus and human immunodeficiency virus in a state of relative calm, no disease outbreak, that is, in a medical "immune Period of tolerance. " With the host immune system constantly increased, the body's immune system gradually began to identify hepatitis B virus and its clearance to enter medical "removal of the immune period." This time the virus replication and host immune confrontation between the on-going process. If the host can not be completely immune powerful enough to control the virus, the virus continued for 6 months who have not yet been cleared for the development of chronic hepatitis B virus infection. Patients can not fully suppress the host immune virus replication, the virus removal process as a see-saw in the war, continuing the see-saw process leading to damage to liver cells. As a result, for the treatment of hepatitis B patients to pay attention to not only inhibit virus replication, the need to regulate the immune host for the disease continued to ease. Correct understanding of the disease with a normal life Hepatitis B virus is the major route of transmission of blood and body fluids such as blood transfusions, surgery, injections, to share with teeth, such as razor may have come into contact with contaminated blood virus, so the current guidelines are recommended for high-risk groups should be vaccinated with hepatitis B vaccine In order to be effective against hepatitis B viruses. At the same time, countries have more stringent screening of blood donors, blood transfusion and blood products caused by the hepatitis B infection has also been a few. In China, hepatitis B transmission is the main way to mother to child transmission, that is, by the hepatitis B virus with the mother transmitted to their children, the process is usually due to contact with the birth mother's hepatitis B positive blood and body fluids due to . As the neonatal immune system is not yet mature, in the hepatitis B virus infection after the virus is difficult to remove, and thus suffer from chronic Hepatitis B high risk, usually as high as 90%; and adults infected with the hepatitis B virus, the immune system due to the body than Strong, and generally able to completely clear the virus, its chronic to the possibility of less than 10%. It should be noted that, as in patients with urine, feces, sweat, tears, the milk of hepatitis B virus were very low, so the day-to-day life or in the process of contact, such as shaking hands, hugging, sharing a dormitory, In a restaurant meal with shared bathrooms and no exposure to blood contact, not the transmission of hepatitis B virus. We need not refuse to hepatitis B patients at arm's length. At the same time, along with the development of medicine, a variety of new antiviral drugs used in clinical treatment, the effect has also made considerable progress in hepatitis B patients as long as the correct understanding of the disease, a doctor with the appropriate choice of anti-viral treatment, most of them can effectively control the disease Development of the normal work and life.

It is reported that in recent days, 90 patients with liver cancer have a history of hepatitis B, hepatitis B have been suffering from the disease than others, the risk of liver cancer as much as 10.7 times that of people suffering from hepatitis B virus to carry the risk of liver cancer is a healthy population of 6.37 Times! Why hepatitis B virus is prone to lead to liver cancer? In a few days ago with "viral hepatitis and hepatocellular carcinoma in Asia" as the theme of the 17th annual meeting of liver disease in the Asia Pacific region, China, South Korea, Japan, Australia and the Asia-Pacific region, such as liver disease prevention and control large number of experts and scholars opened this "The answer." Patients: non-standard treatment of hepatitis B liver change 51-year-old Mr. Zhang Huan Yigan for 12 years, long-term use of certain drugs, he resistance occurred, resulting in a rebound condition. Recently, the company's business in a row because of his business, entertainment, Tilibuzhi feeling, liver pain, quickly check to the hospital, doctors said reluctantly, has advanced liver cancer, missed the best time for treatment ... ... It is understood that similar Cases are not uncommon, due to irregular treatment, combined with the liver and neglect their own health, many patients with hepatitis B unknowingly "shot", the change of hepatitis B liver cancer, died in the tragedy of young elite frequent. Experts say that 90% of patients with liver cancer have a history of hepatitis B, hepatitis B virus infection continued to suffer from liver cancer is the main reason. Such patients are similar to the performance of the following: laboratory examination is "Dasan Yang" or "Xiao Sanyang", normal liver function; liver cancer before the disease was found hidden, no obvious symptoms, liver or no sign of any discomfort zone ... ... The performance of both doctors and patients to a knock on the alarm: hepatitis B patients in a timely manner, if not the norm hospital treatment, away from liver cancer may be just one step away! Experts: more choice of drugs should be cautious "Scientific and standardized treatment is effective in preventing hepatitis B into the key to liver cancer. Hepatitis B need individualized treatment, medication, doctors also need to adjust the anti-viral treatment." At the 17th Asia-Pacific region liver The annual meeting of the disease, experts said, have developed anti-HBV drugs, has formed a nucleoside (acid) analogues, the two long-acting interferon drugs to choose from. In the face of an increased range of drugs, experts say patients should be careful to choose, the 2007 edition of "Guide to Prevention of Hepatitis B" is the international treatment of chronic hepatitis B treatment in the field of the latest regulatory guidance documents, with a high reference value. "Guide" recommends that the nucleoside untreated patients, treatment from the very beginning it is necessary to preferred anti-virus capability, the low rate of drug resistance, and should ensure that the medication compliance, thereby reducing the incidence of drug resistance. Choose from based on the best evidence in support of evidence-based medicine, but also to consider the price of drugs as well as the cost difference between the way (such as medical insurance, at their own expense, etc.). China's renowned liver expert, Shanghai Huashan Hospital, Professor Weng Xinhua that the need for a clear understanding that "we should not only anti-virus capability, but also easy to take and the low rate of drug resistance and side effects of small and cheap prices, such an ideal drug , There is no market. " Reminder: hepatitis B liver cancer become big incentive to open If you are infected with the hepatitis B virus, or your doctor is a hepatitis B patients have to bear in mind the following 4:00 away from the risk factors in order to stay away from hepatocarcinoma invasion: 1. Drink. Long-term drinking of hepatitis B surface antigen-positive can promote the occurrence of liver cirrhosis or liver cancer; 2. Rotten food oil. Well-worn animal and plant oil is toxic and may cause cancer; 3. Moldy food to eat. When they find food, oil, dairy products have mold contamination, the ban on consumption; 4. Let matters drift. Hepatitis B patients and their families to the hospital on a regular basis should be checks on a regular basis to review serum aminotransferase, six months to a year "half-and-half", once a fetus fetal globulin, an annual inspection super-B. Otherwise, let matters drift, persistent infection of hepatitis B virus replication, inflammation to fibrosis of the lesion, will inevitably lead to cirrhosis or liver cancer incidence.

Hepatitis B patients can get married and have children carry large Xiao Sanyang only reflect the situation of HIV Many people think that hepatitis B is a contagious disease and should stay away from those sources of infection. In fact, hepatitis B is not so terrible, not by any means hepatitis B can be transmitted on, so we should not discriminate against hepatitis B carriers. "Xiao Sanyang," only reflects the situation of the virus Q: I would like to consult, "Dasan Yang" and "Xiao Sanyang," What's the difference? A: The so-called "Xiao Sanyang" means "antigen of hepatitis B 2 pairs of semi-inspection" of the two different results. 2 pairs of half of the first pair refers to the surface antigen (HBsAg) and surface antibody (anti-HBs), the second right yes E antigen (HBeAg) and E antibody (anti-HBe), another third on this core antibody ( Anti-HBc) and core antigen (HBcAg). As the cells in the liver, the heart of antigen has been assembled into a full hepatitis B virus, the serum is not free of the core antigen, so they are around in the blood can only be detected on the third and a half in the right, that is, the core antibody, so that 2 pairs And a half. "Dasan Yang" refers to the surface antigen, E antigen and core antibody were positive. It is generally believed, "Dasan Yang," the relative strength of infectious and at the same time develop into chronic hepatitis B is also the possibility of more. "Xiao Sanyang" refers to the surface antigen, E antibody and core antibody were positive. "Dasan Yang," and it is the difference between the former E antigen positive. It is usually from "Da Sanyang" change from the human body is against E antigen produced a certain degree of immunity. It is generally believed, "Xiao Sanyang" less infectious. But for some of the E and E antigen antibody were negative, it may be infected with the hepatitis B virus is already infected with mutant strains of the virus, which can not be expressed by E and E antigen antibody, but if you check hepatitis B virus DNA ribose Nucleic acid is still positive, that the existence of viremia, is still infectious. No matter, "Dasan Yang" or "Xiao Sanyang," only reflect the human body to carry the virus, the situation can not be reflected in the normal liver function or not, and therefore can not be used to determine the severity of the disease. In order to understand the situation in liver function, preferably on a regular basis (3 months to 6 months) to the hospital for a liver function and hepatitis B two pairs of semi-check. Hepatitis B patients can get married Q: I would like some advice, too, if a liver disease, can not be like normal people, like marriage, children's health? A: Hepatitis B patients can get married, of course, there is no provision can not be married. As long as the right to take measures to block and is also able to reproductive health of the baby. Male patients with hepatitis of the newborn less affected, and in patients with hepatitis in pregnant women, through mother to child transmission, the hepatitis B virus to their children. However, through the birth within 24 hours of playing pin the first hepatitis B immune globulin and the hepatitis B vaccine 10ug (in different parts of the body), the sooner the better; and then over a month and 6 months respectively, and then Two more shot injection. This efficient method of blocking up to 85% to 95%, but can not say 100%. After 3 years to strengthen the immune 1 vaccine Q: How long does hepatitis B vaccine injection is better? A: Hepatitis B vaccination after the antibody levels decreased gradually over time. General vaccination, the injection needle 3, after a month of 97% of people would be able to test the antibodies on the surface; the first 2 years remained at this level; dropped to No. 3 in about 74%, antibody titers also fell. Once again the need for vaccination, mainly in the determination of hepatitis B surface antibody titers, to decide when to play hepatitis B vaccine. Hepatitis B surface antibody titers equal to or less than 10 IU / ml, should be inoculated within six months, the antibody titers of greater than 10 IU / ml in 6 years, multiple cropping. Most of the scholars in China within 3 years after immunization recommendations to strengthen the 1st better.

Year of the Pig birth of an upsurge of "catch up" to describe is not an exaggeration. However, in the face of brewing time, "Rob-B-Hood", a number of hepatitis B mothers how it was also not happy with. Maiqi bottle of milk, nutrition supplement of folic acid, but their bodies do not seem to have the perfect preparation. "B" virus is usually spread through exchange of body fluids, including vertical transmission between mother and child play an important role. Statistics show that among the crowd of about 40% HBsAg-positive mother to child transmission is caused. In our country, "B" virus infection among about 6 million women. Therefore, the hepatitis B virus carried by women, from a planned pregnancy, pre-pregnancy health checks to the need to accept scientific guidance and careful plan must not be careless in haste. [A pre-Memo] Hepatitis B common sense to know For chronic hepatitis B, we need to master the basic knowledge of what? In this regard, the capital of Beijing Medical University hospital liver disease friendship Research Professor Jia Jidong, director of the Center, 2002 National Hepatitis B serum epidemiological survey showed that China's chronic hepatitis B in the general population of about 30,000,000 cases, die every year And hepatitis B-related liver disease in about 300,000 cases. Hepatitis B is usually spread in the following ways: the dissemination of blood and blood products; mother to child transmission (perinatal period in which the dissemination of mother to child transmission is the main way for more access to birth HBV-positive mother's blood and body fluids); damaged by the Skin and mucous membrane spread; not strict disinfection of medical equipment, syringes; invasive surgical operations and treatment; intravenous drug abuse; sexual contact, and so on. [Pre-secondary Memo] Science and early detection screening The potential risk of pregnant women suffering from hepatitis B, doctors must determine their own under the guidance of the current situation of hepatitis B patients. If it is simply "HBsAg" positive, or "Xiao Sanyang", and hepatitis B virus DNA (HBV-DNA) negative, that the virus in the body in a steady state. Although this type of virus can be carried for life, do not affect the normal life, so this type of pregnant women. If the diagnosis shows that the "Da Sanyang," At the same time, HBV-DNA positive, then there is obviously infectious, and may also be associated with liver cell injury. The study by pregnant women HBsAg, "hepatitis B" e antigen-positive at the same time, almost 100% of neonatal infection, and most of them become chronic carriers. As a result, women such a good idea to consider the treatment of rest, to be the "B" virus e antigen, HBV-DNA negative for good after pregnancy. In addition, the acute phase of hepatitis C and cirrhosis can not be pregnant after childbirth, chronic hepatitis B should not be pregnant, which is to the health of the mother and at the same time to avoid pregnancy will be transmitting the virus to the fetus. [Three-level pre-Memo] Nissan found in time to avoid the risk of If pregnant women belonging to the liver disease itself, the high-risk groups, then as soon as possible to receive prenatal care is essential. While a normal pregnancy will not increase the damage to the liver, but a number of obstetric complications, such as gravidarum, hypertension during pregnancy, may lead to serious liver disease. To start earlier inspection, early detection and help to deal with the disease, to avoid or mitigate its further development. Once diagnosed, for the treatment of hepatitis B should be a two-pronged, potent inhibition and virus e antigen seroconversion equally important. For example, under the guidance of doctors choose to telbivudine, such as drug treatment. In addition, some of the symptoms of hepatitis B and certain physiological responses during pregnancy and other liver and gallbladder diseases are very similar, the same would develop fever, weakness, oil tired, nausea, vomiting, anorexia, right upper quadrant pain, yellow skin and eyes, and so on, so Hepatitis B in pregnant women, early pregnancy (3 months) to go to hospital for treatment, rule out the possibility of the existence of the disease.

It does not matter to eat together, do not share toothbrushes, razors, etc. "Doctors, patients with hepatitis B and I eat rice, will not be infected with hepatitis B virus?" "Doctors, patients with hepatitis B and I lived together, as if infected with the hepatitis B virus." On the mere mention of these people who came to the hepatitis B digestive internal medicine consultation, for fear that their infected with the hepatitis B virus in Henan Province People's Hospital director Dr. YANG Yu-xiu said that the health concerns is a good thing, but on some unreasonable to ask. Hepatitis B virus of the most dangerous route of transmission was human blood and body fluids. Patients with hepatitis B and eat together, except in patients with the virus in saliva get food, you have been eating into the mouth, and you just suffering from mouth ulcers, which also happens to the virus in the ulcer site, you can be infected with hepatitis B Virus. Mother to child transmission are in the process of birth mothers have the virus in the body fluids into the child in the child inside her mother's nutrition absorption, it is normal for the majority. Foreign scholars have made an interesting experiment. Two gorillas, one carrying hepatitis B virus, no one, Huan Yigan gorillas stomach food transferred to a normal gorilla of the stomach, only to wait until the normal gorilla to digest the food, did not It was detected in the blood of hepatitis B virus. However, the danger is that with a toothbrush to brush their teeth Huanyi Gan gorilla, the toothbrush is not treated, and then it is normal for the gorillas brush their teeth as a result, it's normal gorillas have unfortunately been infected by hepatitis B virus. This reminds us of the experiment, and do not have to live with hepatitis B patients make a fuss, and patients should be careful not to share toothbrushes, razors, and other body fluids and blood can lead to the spread of dangerous goods can be a

In general, hepatitis B mainly through blood, sex and mother-to-child transmission of the three, will not touch the daily life of the transmission. Many people believe that hepatitis B virus is not spread by the intestinal tract, that is, patients with hepatitis B virus carriers, or a total of meals will not be infected. However, clinically found that patients infected with hepatitis B part of the reason is indeed related to eating. Some patients with hepatitis B and the total meal occurred in the more unsanitary hotel or the street after the dinner table. Research shows that when people eat in the hepatitis B virus carriers, the traditional way of eating hepatitis B infection rate of 42%, while the rate of infection of hepatitis B Fencan system for 17%, which shows that hepatitis B is likely to digest Road-borne. In fact, the route of transmission of hepatitis B virus is more complex, people living with HIV or hepatitis B patients with a variety of body fluids are infectious, and its mode of transmission through blood transfusion and blood products, drug injection and acupuncture, and so on. If the medical equipment was contaminated after the hepatitis B virus is not thoroughly sterilized, so in the stomach, Enteroscopy, extraction, cleaning teeth, interventional treatment, surgery and anesthesia, such as intubation may cause the spread of hepatitis B virus. Hepatitis B virus is spread through the digestive tract? When hepatitis B patients and virus carriers or meal together, if your mouth was stabbed fishbone, the teeth bite through, the intestinal mucosa was rough cut of food, or suffering from mouth ulcers, gum bleeding, gastrointestinal Ulcer diseases such as hepatitis B virus gives an opportunity: The damaged mucosa into the blood, leading to infection. In fact, this is a form of blood-borne. When patients or carriers of hepatitis B and dinner, if you can guarantee your mucous membrane of the digestive system is complete, there is no damage, is generally not the hepatitis B infection. However, the gastrointestinal mucosa of the damage is often not easy to find, no one can guarantee their own did not damage the digestive tract, the food-borne disease through a total of the possibility of a great deal. Social life is an important content, but not entirely to the prevention of hepatitis B and the total meal is not possible. The best way to prevent hepatitis B vaccination is with hepatitis B vaccine, once you have had a hepatitis B antibody, the meal can be a total of infected to minimize the opportunity.